Genzyme in the UK

Our Treatment Areas

Abdominal Surgery

Adhesions: A common abdominal surgery complication

What are Adhesions?


Adhesions are fibrous bands that connect tissue surfaces that are normally separated. Adhesion formation is a natural consequence of surgery as the body begins to heal, but it can cause significant complications for the patient. For example, following an abdominal surgery, adhesions may form between an incision in the abdominal wall and the small bowel, causing an obstruction in the small bowel. This type of adhesion often leads to additional surgical procedures to remove the obstruction.

Adhesions develop in 93% of patients following abdominal and pelvic surgery. Abdominal and pelvic surgery include procedures such as hernia repair, gynaecological surgeries, colorectal surgeries, and many others.

How Adhesions Effect a Patient


Adhesions can lead to serious complications including:

  • small bowel obstruction
     
  • female infertility
     
  • chronic debilitating pain
     
  • difficulty with future operations

The consequences of adhesions can be substantial. Post-surgical adhesions cause up to 74% of bowel obstructions and are responsible for 20-50% of chronic pelvic pain cases. Adhesions also are a leading cause for female infertility, causing 15-20% of cases.

Quite often a patient will undergo surgery to cut adhesions, only to have them re-form. Re-operations are also complicated by adhesions. Surgeons have to spend a considerable amount of time, anywhere from 10 minutes to several hours, cutting adhesions before the new procedure can begin. This can prolong the patient's recovery time and increase the risk, cost and complexity of the surgery.

Genzyme Biosurgery has developed biomaterial products used to improve the outcome of surgeries. These are:

  • Seprafilm IITM  Adhesion Barrier
     
  • SeprameshTM Hernia Adhesion Barrier

Contact Info:

Genzyme Therapeutics Ltd
4620 Kingsgate
Cascade Way
Oxford Business Park South
Oxford
OX4 2SU
Tel: +01865 405200
Fax: +01865 774172
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Email

Genzyme Therapeutics Ltd, Genzyme Europe Research
310 Cambridge Science Park
Milton Road
Cambridge
CB4 0WG
Tel: +01223 394000
Fax: +01223 394190
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Genzyme Ltd, Haverhill Operations
12 Rookwood Way
Haverhill
Suffolk
CB9 8PU
Tel: +01440 703522
Fax: +01440 716269
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